2022 American Transplant Congress
The Post-operative Clinical Outcomes Of 59 Tanrp Cases In An International Cohort
*Purpose: Heart transplantation is an immensely effective service and is currently the only definitive treatment for heart failure. However, transplantation is limited by donor availability.…2022 American Transplant Congress
Cardiomyocyte Cross-Sectional Area Increases After Orthotopic Cardiac Xenotransplantation and is Not Likely a Significant Contributor to Xenograft Growth up to 9 Months
*Purpose: Genetically engineered (GE) pigs are thought to be an alternative organ source for patients in end-stage heart failure unable to receive a timely allograft.…2022 American Transplant Congress
Post Heart Transplant Outcomes of Desensitized Durable Mechanical Circulatory Support Patients
*Purpose: Desensitization therapy (DST) is considered to increase the chances of a negative crossmatch, to expand the number of suitable donors, and to improve post-transplant…2022 American Transplant Congress
Direct Procurement of Heart and Lungs from a Controlled DCD Donor with Ongoing Abdominal Normothermic Regional Perfusion (aNRP) – A Synchronized Retrieval
*Purpose: With the increased number of aNRP in controlled DCD donors comes a high demand for techniques to directly procure cardiothoracic organs during the aNRP.…2022 American Transplant Congress
Using mTOR Inhibitor Nanoimmunotherapy to Induce Cardiac Allograft Tolerance in Non-Human Primates
*Purpose: Though tolerance of kidney allografts has been consistently achieved using a mixed-chimerism model, cardiac allografts remain resistant to tolerance induction. Lipoprotein-based nanobiologics loaded with…2022 American Transplant Congress
Pre-Emptive Rituximab Use for Epstein-Barr Virus (EBV) Viremia in Cardiothoracic Solid Organ Transplant Recipients
University of Chicago Medicine, Chicago, IL
*Purpose: EBV viremia is associated with potentially life-threatening post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation. The utility of rituximab for treating EBV viremia in…2022 American Transplant Congress
Status Exception Use in the New Seven-Tiered Heart Allocation System
*Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
Fontan versus Non-Fontan Combined Heart-Liver Transplantation: Proceed but Cautiously
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Combined heart-liver transplantation (CHLT) is increasing, corresponding with a growing prevalence of Fontan-associated end-organ damage. We aimed to describe our contemporary institutional experience with…2022 American Transplant Congress
Cryptococcal Meningitis Presenting as SIADH in a Heart Transplant Recipient
Temple University Hospital, Philadelphia, PA
*Purpose: Cryptococcal meningitis is a potentially fatal invasive fungal infection in solid organ transplant recipients. Meningoencephalitis is the most common clinical manifestation of cryptococcal infection.…
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